n–3 polyunsaturated fatty acids in the maternal diet modify the postnatal development of nervous regulation of intestinal permeability in piglets
F De Quelen, J Chevalier… - The Journal of …, 2011 - Wiley Online Library
F De Quelen, J Chevalier, M Rolli‐Derkinderen, J Mourot, M Neunlist, G Boudry
The Journal of physiology, 2011•Wiley Online LibraryNon‐technical summary In this study, we demonstrated that supplementation of the maternal
diet with a particular fatty acid, 18: 3 n‐3, the precursor of the n‐3 fatty acid family, modified
intestinal permeability, probably via diet‐induced neuroplastic changes of the enteric
nervous system of newborn piglets. These findings suggest that feeding fatty acids of the n‐3
family during pregnancy and lactation impact newborn intestinal barrier function. However,
the beneficial versus harmful consequences of this increased intestinal permeability remain …
diet with a particular fatty acid, 18: 3 n‐3, the precursor of the n‐3 fatty acid family, modified
intestinal permeability, probably via diet‐induced neuroplastic changes of the enteric
nervous system of newborn piglets. These findings suggest that feeding fatty acids of the n‐3
family during pregnancy and lactation impact newborn intestinal barrier function. However,
the beneficial versus harmful consequences of this increased intestinal permeability remain …
Non‐technical summary In this study, we demonstrated that supplementation of the maternal diet with a particular fatty acid, 18:3 n‐3, the precursor of the n‐3 fatty acid family, modified intestinal permeability, probably via diet‐induced neuroplastic changes of the enteric nervous system of newborn piglets. These findings suggest that feeding fatty acids of the n‐3 family during pregnancy and lactation impact newborn intestinal barrier function. However, the beneficial versus harmful consequences of this increased intestinal permeability remain to be elucidated.
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