Publisher Summary Lysyl oxidase (LOX) is a copper-containing amine oxidase belonging to
a heterogeneous family of enzymes that oxidize primary amine substrates to reactive
aldehydes. It has been traditionally known for one function—the extracellular catalysis of
lysine-derived cross-links in fibrillar collagens and elastin. Diverse roles have been
attributed to lysyl oxidase and its novel activities cover a spectrum of diverse biological
functions, such as developmental regulation, tumor suppression, cell motility, and cellular …