[HTML][HTML] Characterization of collagenous peptides bound to lysyl hydroxylase isoforms
M Risteli, O Niemitalo, H Lankinen, AH Juffer… - Journal of Biological …, 2004 - ASBMB
Lysyl hydroxylase (LH, EC 1.14. 11.4) is the enzyme catalyzing the formation of hydroxylysyl
residues in collagens and other proteins with collagenous domains. Although lower species,
such as Caenorhabditis elegans, have only one LH orthologue, LH activity in higher
species, such as human, rat, and mouse, is present in three molecules, LH1, LH2, and LH3,
encoded by three different genes. In addition, LH2 is present in two alternatively spliced
forms (LH2a, LH2b). To understand the functions of the four molecular forms of LH in …
residues in collagens and other proteins with collagenous domains. Although lower species,
such as Caenorhabditis elegans, have only one LH orthologue, LH activity in higher
species, such as human, rat, and mouse, is present in three molecules, LH1, LH2, and LH3,
encoded by three different genes. In addition, LH2 is present in two alternatively spliced
forms (LH2a, LH2b). To understand the functions of the four molecular forms of LH in …
