The inflammatory wound healing response of the central nervous system (CNS) following
mechanical injury is characterized by at least one or two phases of T cell infiltration.
Surprisingly, whether T cells play a beneficial or detrimental role in these processes is still
controversial. It has been suggested that autoimmune T cells may provide “protective
autoimmunity”, however, after CNS injury, injections of autoimmune T cells and vaccine
strategies led to both improvement in some models and exacerbation of the damage in …