[PDF][PDF] Expression Signature of E2F1 and Its Associated Genes Predict Superficial to Invasive Progression of Bladder Tumors

JS Lee, SH Leem, SY Lee, SC Kim… - Journal of clinical …, 2010 - researchgate.net
JS Lee, SH Leem, SY Lee, SC Kim, ES Park, SB Kim, SK Kim, YJ Kim, WJ Kim, IS Chu
Journal of clinical oncology, 2010researchgate.net
Purpose In approximately 20% of patients with superficial bladder tumors, the tumors
progress to invasive tumors after treatment. Current methods of predicting the clinical
behavior of these tumors prospectively are unreliable. We aim to identify a molecular
signature that can reliably identify patients with high-risk superficial tumors that are likely to
progress to invasive tumors.
Purpose
In approximately 20% of patients with superficial bladder tumors, the tumors progress to invasive tumors after treatment. Current methods of predicting the clinical behavior of these tumors prospectively are unreliable. We aim to identify a molecular signature that can reliably identify patients with high-risk superficial tumors that are likely to progress to invasive tumors.
researchgate.net