The pharmacology of mTOR inhibition
DA Guertin, DM Sabatini - Science signaling, 2009 - science.org
Science signaling, 2009•science.org
A flurry of reports indicates that we are entering a new phase in the development of
mammalian target of rapamycin (mTOR)–based therapies for oncology. Here, we summarize
exciting findings regarding mTOR signaling and the outlook for mTOR inhibitors as tools to
study the mTOR pathway and as drugs in the clinic.
mammalian target of rapamycin (mTOR)–based therapies for oncology. Here, we summarize
exciting findings regarding mTOR signaling and the outlook for mTOR inhibitors as tools to
study the mTOR pathway and as drugs in the clinic.
A flurry of reports indicates that we are entering a new phase in the development of mammalian target of rapamycin (mTOR)–based therapies for oncology. Here, we summarize exciting findings regarding mTOR signaling and the outlook for mTOR inhibitors as tools to study the mTOR pathway and as drugs in the clinic.
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