Ultraviolet light and cutaneous lupus
M Bijl, CGM Kallenberg - Lupus, 2006 - journals.sagepub.com
M Bijl, CGM Kallenberg
Lupus, 2006•journals.sagepub.comExposure to ultraviolet (UV) light is one of the major factors known to trigger cutaneous
disease activity in (systemic) lupus erythematosus patients. UV light, UVB in particular, is a
potent inducer of apoptosis. Currently, disturbed clearance of apoptotic cells is one of the
concepts explaining the development of inflammation in lupus patients. We review the role
of apoptotic cells and autoantibodies in the pathogenesis of UVB induced skin lesions.
disease activity in (systemic) lupus erythematosus patients. UV light, UVB in particular, is a
potent inducer of apoptosis. Currently, disturbed clearance of apoptotic cells is one of the
concepts explaining the development of inflammation in lupus patients. We review the role
of apoptotic cells and autoantibodies in the pathogenesis of UVB induced skin lesions.
Exposure to ultraviolet (UV) light is one of the major factors known to trigger cutaneous disease activity in (systemic) lupus erythematosus patients. UV light, UVB in particular, is a potent inducer of apoptosis. Currently, disturbed clearance of apoptotic cells is one of the concepts explaining the development of inflammation in lupus patients. We review the role of apoptotic cells and autoantibodies in the pathogenesis of UVB induced skin lesions.
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