[HTML][HTML] Fatty liver accompanies an increase in lactobacillus species in the hind gut of C57BL/6 mice fed a high-fat diet

H Zeng, J Liu, MI Jackson, FQ Zhao, L Yan… - The Journal of …, 2013 - Elsevier
High-fat (HF) diets can produce obesity and have been linked to the development of
nonalcoholic fatty liver disease and changes in the gut microbiome. To test the hypothesis
that HF feeding increases certain predominant hind gut bacteria and development of
steatohepatitis, C57BL/6 mice were fed an HF (45% energy) or low-fat (LF)(10% energy) diet
for 10 wk. At the end of the feeding period, body weights in the HF group were 34% greater
than those in the LF group (P< 0.05). These changes were associated with dramatic …