Intrathecal chemokine synthesis in mild cognitive impairment and Alzheimer disease
D Galimberti, N Schoonenboom, P Scheltens… - Archives of …, 2006 - jamanetwork.com
Background Immunoreactivity for several chemokines and for their related receptors has
been demonstrated in resident cells of the central nervous system, and the up-regulation of
some of them is associated with pathological changes found in Alzheimer disease (AD).
Objective To determine interferon-γ-inducible protein 10 (IP-10), monocyte chemotactic
protein 1 (MCP-1), and interleukin 8 (IL-8) levels in cerebrospinal fluid (CSF) from subjects
with amnestic mild cognitive impairment (MCI) and patients with AD as compared with age …
been demonstrated in resident cells of the central nervous system, and the up-regulation of
some of them is associated with pathological changes found in Alzheimer disease (AD).
Objective To determine interferon-γ-inducible protein 10 (IP-10), monocyte chemotactic
protein 1 (MCP-1), and interleukin 8 (IL-8) levels in cerebrospinal fluid (CSF) from subjects
with amnestic mild cognitive impairment (MCI) and patients with AD as compared with age …