Heart failure has reached epidemic proportions among the elderly, in whom it is most often attributable to an ischemic cardiomyopathy (ICM) with previous myocardial infarction (s)(MIs). The infarcted heart is a “house divided”(1), its myocardium disrupted by the loss of necrotic cardiomyocytes, its structural syncytium interrupted by an infarct scar, and its remaining viable myocardium corrupted by an interstitial fibrosis. Multiple foci of replacement fibrosis, in combination with interstitial fibrosis, are reported to be the major cause of ventricular remodeling in the cardiomyopathic heart of ischemic origin, where it accounts for nearly 70% of fibrotic tissue; infarction (scar) comprises 30%(2).