Autophagic lysosome reformation

Y Chen, L Yu - Experimental cell research, 2013 - Elsevier
Y Chen, L Yu
Experimental cell research, 2013Elsevier
Autophagy is an evolutionarily conserved lysosome-dependent degradation pathway. In
recent years, many important advances have been made in understanding the cellular and
molecular mechanism of autophagosome formation. However, the late stages of autophagy—
the cellular events after formation of the autolysosome—are relatively rarely studied. In this
review, we discussed the cellular process and molecular mechanism of autophagic
lysosome reformation, a cellular events which defines the terminal stage of autophagy.
Autophagy is an evolutionarily conserved lysosome-dependent degradation pathway. In recent years, many important advances have been made in understanding the cellular and molecular mechanism of autophagosome formation. However, the late stages of autophagy—the cellular events after formation of the autolysosome—are relatively rarely studied. In this review, we discussed the cellular process and molecular mechanism of autophagic lysosome reformation, a cellular events which defines the terminal stage of autophagy.
Elsevier