Genomics in multiple sclerosis—current state and future directions

M Comabella, R Martin - Journal of neuroimmunology, 2007 - Elsevier
Microarray-based gene expression profiling of large numbers of genes or even the whole
genome has only recently become possible. Several studies have employed this technology
in multiple sclerosis (MS) and its animal model, experimental allergic encephalomyelitis
(EAE), and although results are promising, microarray-based genomics research is still
viewed with skepticism. It is often negatively perceived as a fishing expedition rather than a
discovery-oriented effort that takes into account the immense complexity of diseases such as …