[HTML][HTML] Functional interaction of common allergens and a C-type lectin receptor, dendritic cell-specific ICAM3-grabbing non-integrin (DC-SIGN), on human dendritic …

SC Hsu, CH Chen, SH Tsai, H Kawasaki… - Journal of Biological …, 2010 - ASBMB
Fucosylated glycans on pathogens are known to shape the immune response through their
interaction with pattern recognition receptors, such as C-type lectin receptors (CLRs), on
dendritic cells (DCs). Similar fucosylated structures are also commonly found in a variety of
allergens, but their functional significance remains unclear. To test a hypothesis that
allergen-associated glycans serve as the molecular patterns in functional interaction with
CLRs, an enzyme-linked immunosorbent assay-based binding assay was performed to …