Identification of 7α-hydroxy-3-oxo-4-cholestenoic acid in chronic subdural hematoma
K Nagata, K Takakura, T Asano, Y Seyama… - … et Biophysica Acta (BBA …, 1992 - Elsevier
We detected a novel kind of bile acid in the content of chronic subdural hematoma. This
substance was specifically found in chronic subdural hematoma, and not in subdural
hygroma, which is pathologically similar except for the lack of capsular membrane. The
compound was identified as 7α-hydroxy-3-oxo-4-cholestenoic acid by high performance
liquid chromatography, gas chromatography-mass spectrometry, and nuclear magnetic
resonance spectrometry. The structure was confirmed by the comparison with the chemically …
substance was specifically found in chronic subdural hematoma, and not in subdural
hygroma, which is pathologically similar except for the lack of capsular membrane. The
compound was identified as 7α-hydroxy-3-oxo-4-cholestenoic acid by high performance
liquid chromatography, gas chromatography-mass spectrometry, and nuclear magnetic
resonance spectrometry. The structure was confirmed by the comparison with the chemically …