High prevalence of acquired antimicrobial resistance unrelated to heavy antimicrobial consumption
A Bartoloni, F Bartalesi, A Mantella… - Journal of Infectious …, 2004 - academic.oup.com
A Bartoloni, F Bartalesi, A Mantella, E Dell'Amico, M Roselli, M Strohmeyer, HG Barahona…
Journal of Infectious Diseases, 2004•academic.oup.comIn a very remote rural Bolivian community where the use of antimicrobials has been minimal
and where exchanges with the exterior are very limited, 67% of subjects were found to be
carriers of fecal Escherichia coli with acquired resistance to⩾ 1 antimicrobial agent (s); the
highest rates were observed for tetracycline (64%), ampicillin (58%), trimethoprim-
sulfamethoxazole (50%), and chloramphenicol (41%). The most relevant implication of these
findings is that, in certain settings, the spread and maintenance of antimicrobial resistance …
and where exchanges with the exterior are very limited, 67% of subjects were found to be
carriers of fecal Escherichia coli with acquired resistance to⩾ 1 antimicrobial agent (s); the
highest rates were observed for tetracycline (64%), ampicillin (58%), trimethoprim-
sulfamethoxazole (50%), and chloramphenicol (41%). The most relevant implication of these
findings is that, in certain settings, the spread and maintenance of antimicrobial resistance …
Abstract
In a very remote rural Bolivian community where the use of antimicrobials has been minimal and where exchanges with the exterior are very limited, 67% of subjects were found to be carriers of fecal Escherichia coli with acquired resistance to ⩾1 antimicrobial agent(s); the highest rates were observed for tetracycline (64%), ampicillin (58%), trimethoprim-sulfamethoxazole (50%), and chloramphenicol (41%). The most relevant implication of these findings is that, in certain settings, the spread and maintenance of antimicrobial resistance can occur, regardless of whether selective pressure generated by the use of antimicrobials is present.
Oxford University Press