An ELISA for hCAP-18, the cathelicidin present in human neutrophils and plasma

O Sørensen, JB Cowland, J Askaa… - Journal of immunological …, 1997 - Elsevier
hCAP-18 is a newly described protein of human neutrophilic granulocytes which belongs to
the cathelicidin family of antimicrobial proteins. Members of this protein family share a
common N-terminal sequence followed by a highly diverse antimicrobial, cationic C-
terminus. The present work describes the production of recombinant hCAP-18, the
generation of antibodies to the protein and the development of an accurate, sensitive and
specific ELISA for the detection of hCAP-18 in cells, plasma and urine with a detection limit …