Antiplatelet therapies for the treatment of cardiovascular disease
AD Michelson - Nature Reviews Drug Discovery, 2010 - nature.com
AD Michelson
Nature Reviews Drug Discovery, 2010•nature.comAntiplatelet therapy has been successful in reducing mortality and morbidity in acute
myocardial infarction. Recent advances in understanding the molecular basis of the role of
platelets in cardiovascular thrombosis have enabled the development of new agents with
the potential to further reduce mortality and morbidity. This article reviews the role of
platelets in haemostasis and cardiovascular thrombosis, and discusses the benefits and
limitations of current and investigational antiplatelet agents in the treatment of …
myocardial infarction. Recent advances in understanding the molecular basis of the role of
platelets in cardiovascular thrombosis have enabled the development of new agents with
the potential to further reduce mortality and morbidity. This article reviews the role of
platelets in haemostasis and cardiovascular thrombosis, and discusses the benefits and
limitations of current and investigational antiplatelet agents in the treatment of …
Abstract
Antiplatelet therapy has been successful in reducing mortality and morbidity in acute myocardial infarction. Recent advances in understanding the molecular basis of the role of platelets in cardiovascular thrombosis have enabled the development of new agents with the potential to further reduce mortality and morbidity. This article reviews the role of platelets in haemostasis and cardiovascular thrombosis, and discusses the benefits and limitations of current and investigational antiplatelet agents in the treatment of cardiovascular disease.
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