Changes in the inner and outer retinal layers after acute increase of the intraocular pressure in adult albino Swiss mice

N Cuenca, I Pinilla, L Fernández-Sánchez… - Experimental eye …, 2010 - Elsevier
In adult albino mice the effects of increased intraocular pressure on the outer retina and its
circuitry was investigated at intervals ranging 3–14 weeks. Ocular hypertension (OHT) was
induced by cauterizing the vessels draining the anterior part of the mice eye, as recently
reported (Salinas-Navarro et al., 2009a). Electroretinographic (ERG) responses were
recorded simultaneously from both eyes and compared each other prior to and at different
survival intervals of 2, 8 or 12 weeks after lasering. Animals were processed at 3, 9 or 14 …