A model to measure lymphatic drainage from the eye
M Kim, MG Johnston, N Gupta, S Moore… - Experimental eye …, 2011 - Elsevier
Intraocular pressure (IOP) is the most important risk factor for glaucoma development and
progression. Most anti-glaucoma treatments aim to lower IOP by enhancing aqueous humor
drainage from the eye. Aqueous humor drainage occurs via well-characterized trabecular
meshwork (TM) and uveoscleral (UVS) pathways, and recently described ciliary body
lymphatics. The relative contribution of the lymphatic pathway to aqueous drainage is not
known. We developed a sheep model to quantitatively assess lymphatic drainage along with …
progression. Most anti-glaucoma treatments aim to lower IOP by enhancing aqueous humor
drainage from the eye. Aqueous humor drainage occurs via well-characterized trabecular
meshwork (TM) and uveoscleral (UVS) pathways, and recently described ciliary body
lymphatics. The relative contribution of the lymphatic pathway to aqueous drainage is not
known. We developed a sheep model to quantitatively assess lymphatic drainage along with …