Tissue engineering in head and neck reconstructive surgery: what type of tissue do we need?

UR Goessler, J Stern-Straeter, K Riedel… - European archives of …, 2007 - Springer
UR Goessler, J Stern-Straeter, K Riedel, GM Bran, K Hörmann, F Riedel
European archives of oto-rhino-laryngology, 2007Springer
Craniofacial tissue loss due to congenital defects, disease or injury is a major clinical
problem. The head and neck region is composed of several tissues. The most prevalent
method of reconstruction is autologous grafting. Often, there is insufficient host tissue for
adequate repair of the defect side, and extensive donor site morbidity may result from the
secondary surgical procedure. The field of tissue engineering has the potential to create
functional replacements for damaged or pathologic tissues.
Abstract
Craniofacial tissue loss due to congenital defects, disease or injury is a major clinical problem. The head and neck region is composed of several tissues. The most prevalent method of reconstruction is autologous grafting. Often, there is insufficient host tissue for adequate repair of the defect side, and extensive donor site morbidity may result from the secondary surgical procedure. The field of tissue engineering has the potential to create functional replacements for damaged or pathologic tissues.
Springer