Increased risk of childhood asthma from antibiotic use in early life
AL Kozyrskyj, P Ernst, AB Becker - Chest, 2007 - Elsevier
Background To address the major methodological issues of reverse causation and selection
bias in epidemiologic studies of antibiotic use in early life and the development of asthma,
we undertook a cohort study of this association in a complete population of children.
Methods Using the health-care and prescription databases of Manitoba, Canada, this
longitudinal study assessed the association between antibiotic prescription use during the
first year of life and asthma at age 7 years in a 1995 birth cohort of 13,116 children. Results …
bias in epidemiologic studies of antibiotic use in early life and the development of asthma,
we undertook a cohort study of this association in a complete population of children.
Methods Using the health-care and prescription databases of Manitoba, Canada, this
longitudinal study assessed the association between antibiotic prescription use during the
first year of life and asthma at age 7 years in a 1995 birth cohort of 13,116 children. Results …