PI3Ks in lymphocyte signaling and development

K Okkenhaug, DA Fruman - Phosphoinositide 3-kinase in Health and …, 2011 - Springer
Phosphoinositide 3-kinase in Health and Disease: Volume 1, 2011Springer
Lymphocyte development and function are regulated by tyrosine kinase and G-protein
coupled receptors. Each of these classes of receptors activates phosphoinositide 3-kinase
(PI3K). In this chapter, we summarize current understanding of how PI3K contributes to key
aspects of the adaptive immune system.
Abstract
Lymphocyte development and function are regulated by tyrosine kinase and G-protein coupled receptors. Each of these classes of receptors activates phosphoinositide 3-kinase (PI3K). In this chapter, we summarize current understanding of how PI3K contributes to key aspects of the adaptive immune system.
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