Tumor-associated stromal cells expressing E-prostanoid 2 or 3 receptors in prostate cancer: correlation with tumor aggressiveness and outcome by angiogenesis and …

Y Miyata, K Ohba, T Matsuo, SI Watanabe, T Hayashi… - Urology, 2013 - Elsevier
OBJECTIVE: To clarify the detailed pathologic roles of prostaglandin E2 in prostate cancer
tissues, the present study investigated the clinical significance and prognostic roles of the
density of tumor-associated stromal cells expressing specific receptors for prostaglandin E2,
termed “E-prostanoid (EP) 1-4 receptors (EP1R-4Rs).” METHODS: The expression of each
receptor was immunohistochemically examined in 114 formalin-fixed biopsy specimens.
Correlations with clinicopathologic features were investigated in these specimens …