Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis
RG Knodell, KG Ishak, WC Black, TS Chen, R Craig… - Hepatology, 1981 - journals.lww.com
Abstract A Histology Activity Index has been developed which generates a numerical score
for liver biopsy specimens obtained from patients with asymptomatic chronic active hepatitis.
Biopsies are graded in four categories: periportal necrosis, intralobular necrosis, portal
inflammation, and fibrosis. Under code, three pathologists and three hepatologists evaluated
14 liver biopsy specimens obtained from five patients with asymptomatic chronic active
hepatitis. Good correlation was seen between severity of liver biopsy lesions as judged by …
for liver biopsy specimens obtained from patients with asymptomatic chronic active hepatitis.
Biopsies are graded in four categories: periportal necrosis, intralobular necrosis, portal
inflammation, and fibrosis. Under code, three pathologists and three hepatologists evaluated
14 liver biopsy specimens obtained from five patients with asymptomatic chronic active
hepatitis. Good correlation was seen between severity of liver biopsy lesions as judged by …