[HTML][HTML] Involvement of LMO7 in the association of two cell-cell adhesion molecules, nectin and E-cadherin, through afadin and α-actinin in epithelial cells
T Ooshio, K Irie, K Morimoto, A Fukuhara, T Imai… - Journal of Biological …, 2004 - ASBMB
Nectins are Ca 2+-independent immunoglobulin-like cell-cell adhesion molecules that are
involved in formation of cadherin-based adherens junctions (AJs). The nectin-based cell-cell
adhesion induces activation of Cdc42 and Rac small G proteins, which eventually enhances
the formation of AJs through reorganization of the actin cytoskeleton. Although evidence has
accumulated that nectins recruit cadherins to the nectin-based cell-cell adhesion sites
through their cytoplasm-associated proteins, afadin and catenins, it is not fully understood …
involved in formation of cadherin-based adherens junctions (AJs). The nectin-based cell-cell
adhesion induces activation of Cdc42 and Rac small G proteins, which eventually enhances
the formation of AJs through reorganization of the actin cytoskeleton. Although evidence has
accumulated that nectins recruit cadherins to the nectin-based cell-cell adhesion sites
through their cytoplasm-associated proteins, afadin and catenins, it is not fully understood …