N-syndecan (syndecan 3) from neonatal rat brain binds basic fibroblast growth factor
MA Chernousov, DJ Carey - Journal of Biological Chemistry, 1993 - ASBMB
The cell surface proteoglycan N-syndecan (syndecan 3) was isolated from neonatal rat
brain. Purified brain N-syndecan had biochemical properties very similar to N-syndecan
previously identified in Schwann cells: it contained mainly, if not exclusively, heparan sulfate
glycosaminoglycan chains and had a core protein with an apparent molecular mass of 120
kDa by sodium dodecyl sulfate-gel electrophoresis. We examined the interactions between
purified N-syndecan and extracellular ligands using a solid phase binding assay. It was …
brain. Purified brain N-syndecan had biochemical properties very similar to N-syndecan
previously identified in Schwann cells: it contained mainly, if not exclusively, heparan sulfate
glycosaminoglycan chains and had a core protein with an apparent molecular mass of 120
kDa by sodium dodecyl sulfate-gel electrophoresis. We examined the interactions between
purified N-syndecan and extracellular ligands using a solid phase binding assay. It was …