Overexpression of Cripto and its prognostic significance in breast cancer: a study with long-term survival
YP Gong, PM Yarrow, HL Carmalt, SY Kwun… - European Journal of …, 2007 - Elsevier
INTRODUCTION: Cripto is a founding member of the EGF-CFC family, and plays an
important role in tumourigenesis, tumour cell proliferation and migration. We aimed to
determine the significance of Cripto expression on the survival of patients with breast
cancer. METHODS: Immunohistochemical detection of Cripto was performed by using mAb
C13 on 120 formalin-fixed paraffin-embedded breast tumour specimens in tissue
microarrays. This cohort comprises a series of 120 patients with primary operable breast …
important role in tumourigenesis, tumour cell proliferation and migration. We aimed to
determine the significance of Cripto expression on the survival of patients with breast
cancer. METHODS: Immunohistochemical detection of Cripto was performed by using mAb
C13 on 120 formalin-fixed paraffin-embedded breast tumour specimens in tissue
microarrays. This cohort comprises a series of 120 patients with primary operable breast …