[PDF][PDF] Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility.
K Hiramatsu, H Hanaki, T Ino, K Yabuta… - The Journal of …, 1997 - researchgate.net
In May 1996, a 4 month-old male infant underwent heart surgery for pulmonary atresia. Two
weeks following surgery, the infant became febrile and developed a purulent discharge from
the sternal surgical incision site; culture of the purulent material yielded MRSA. The patient
was treated with vancomycin (45 mg/kg daily) for 29 days, but fever and discharge of pus
continued, and the C-reactive protein (CRP) remained elevated (40 mg/L). The treatment
was changed to a combination of vancomycin and arbekacin (an aminoglycoside approved …
weeks following surgery, the infant became febrile and developed a purulent discharge from
the sternal surgical incision site; culture of the purulent material yielded MRSA. The patient
was treated with vancomycin (45 mg/kg daily) for 29 days, but fever and discharge of pus
continued, and the C-reactive protein (CRP) remained elevated (40 mg/L). The treatment
was changed to a combination of vancomycin and arbekacin (an aminoglycoside approved …