Differential and regulated expression of CXC, CC, and C-chemokines by human colon epithelial cells

SK Yang, L Eckmann, A Panja, MF Kagnoff - Gastroenterology, 1997 - gastrojournal.org
BACKGROUND & AIMS: Intestinal epithelial cells constitute a barrier between host and
external milieu and can play a role in signaling the influx of leukocytes during the acute
mucosal inflammatory response. To further explore this role, the regulated expression of
twelve CXC, CC, and C-chemokines by human colon epithelial cells was characterized.
METHODS: Chemokine production was assessed in HT-29 and Caco-2 human colon
epithelial cells that were infected with Salmonella dublin or stimulated with interleukin 1 …