The heart is a target organ for androgen
HC McGill Jr, VC Anselmo, JM Buchanan, PJ Sheridan - Science, 1980 - science.org
HC McGill Jr, VC Anselmo, JM Buchanan, PJ Sheridan
Science, 1980•science.orgAutoradiographic and biochemical analyses of the hearts of female rhesus monkeys and
baboons indicate that atrial and ventricular myocardial cells contain androgen receptors.
Although the specific effects of nuclear uptake and retention of androgen on the function of
heart muscle cells are not known, the presence of this receptor suggests that sex steroid
hormones may affect myocardial function directly and may explain some of the peculiar
differences in heart disease between men and women.
baboons indicate that atrial and ventricular myocardial cells contain androgen receptors.
Although the specific effects of nuclear uptake and retention of androgen on the function of
heart muscle cells are not known, the presence of this receptor suggests that sex steroid
hormones may affect myocardial function directly and may explain some of the peculiar
differences in heart disease between men and women.
Autoradiographic and biochemical analyses of the hearts of female rhesus monkeys and baboons indicate that atrial and ventricular myocardial cells contain androgen receptors. Although the specific effects of nuclear uptake and retention of androgen on the function of heart muscle cells are not known, the presence of this receptor suggests that sex steroid hormones may affect myocardial function directly and may explain some of the peculiar differences in heart disease between men and women.
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