[PDF][PDF] Endothelin-induced nociception in mice: mediation by ETA and ETB receptors.
RB Raffa, JJ Schupsky, HI Jacoby - Journal of Pharmacology and …, 1996 - Citeseer
RB Raffa, JJ Schupsky, HI Jacoby
Journal of Pharmacology and Experimental Therapeutics, 1996•CiteseerEndothelin-Induced Nociception in Mice: Mediation by ETA and ETB Receptors Page 1 Vol.
276, No. 2 Printed in USA ABSTRACT ABBREVIATIONS: BQ-1 23, cyclo[D-Asp-Pro-D-Val-Leu-D-Trp-];
Er-i ,endothelin-1 ; ET-2, endothelin-2; ET-3, endothelin-3; ET-C, [His-Leu-Asplle-lle-TrpJ;
PpQ, phenyl-p-quinone; S6a, sarafotoxin S6a; S6b, sarafotoxin S6b; S6c, sarafotoxin S6c; [Ala311]ET-1
, endothelin-i with Ala substitutions for Cys3 and . 647 0022.3565/96/2762-0647$03.00/0
THE JOURNAL OF PHARMACOLOGY m EXPERIMENTAL THERAPEUTICS Copyright © …
276, No. 2 Printed in USA ABSTRACT ABBREVIATIONS: BQ-1 23, cyclo[D-Asp-Pro-D-Val-Leu-D-Trp-];
Er-i ,endothelin-1 ; ET-2, endothelin-2; ET-3, endothelin-3; ET-C, [His-Leu-Asplle-lle-TrpJ;
PpQ, phenyl-p-quinone; S6a, sarafotoxin S6a; S6b, sarafotoxin S6b; S6c, sarafotoxin S6c; [Ala311]ET-1
, endothelin-i with Ala substitutions for Cys3 and . 647 0022.3565/96/2762-0647$03.00/0
THE JOURNAL OF PHARMACOLOGY m EXPERIMENTAL THERAPEUTICS Copyright © …
Results
Endothelins. A single ip injection of ET-1, ET-2 or ET-3 to mice reliably elicited a robust and characteristic behavioral response of rapid onset, consistent with previous re-ports (Ferreira et at., 1989; Raffa and Jacoby, 1991). Each of
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