[HTML][HTML] Indirect CD4+ TH1 response, antidonor antibodies and diffuse C4d graft deposits in long-term recipients conditioned by donor antigens priming
C Ballet, K Renaudin, N Degauque, HL Mai… - American Journal of …, 2009 - Elsevier
Priming of recipients by DST induces long-term survival of mismatched allografts in adult
rats. Despite these recipients developing inducible T regulatory cells able to transfer long-
term graft survival to a secondary host, a state of chronic rejection is also observed. We
revisited the molecular donor MHC targets of the cellular response in acute rejection and
analyzed the cellular and humoral responses in recipients with long-term graft survival
following transplantation. We found three immunodominant peptides, all derived from LEW …
rats. Despite these recipients developing inducible T regulatory cells able to transfer long-
term graft survival to a secondary host, a state of chronic rejection is also observed. We
revisited the molecular donor MHC targets of the cellular response in acute rejection and
analyzed the cellular and humoral responses in recipients with long-term graft survival
following transplantation. We found three immunodominant peptides, all derived from LEW …