these disorders directly and indirectly lead to further non-endocrine morbidity. Thus, while monitoring for and managing endocrine disorders in existing cancer survivors, we must continue to investigate new curative cancer treatments that have less potential to cause endocrine and other serious late effects. Several national groups and the International Late Effects of Childhood Cancer Guideline Harmonization Group10 continue to evaluate the evidence systematically and develop clinical guidelines for screening of asymptomatic childhood cancer survivors.