Yes, AKI truly leads to CKD

C Hsu - Journal of the American Society of Nephrology, 2012 - journals.lww.com
In the past few years, there has been a great deal of interest regarding the long-term
sequelae of AKI, including the impact of an episode of AKI on development of incident CKD
or acceleration of pre-existing CKD. In JASN, Rifkin et al. 1 argue that the observed AKI–
CKD associations should be considered noncausal as long as they are based on
epidemiologic or observational studies. I disagree based on the following considerations.