Oxidative stress and galactose-deficient IgA1 as markers of progression in IgA nephropathy

R Camilla, H Suzuki, V Dapra, E Loiacono… - Clinical Journal of the …, 2011 - journals.lww.com
Results Sera from IgAN patients showed higher levels of Gd-IgA1,% HAA, and AOPPs, but
lower levels of SH-Alb in comparison to that from healthy controls. Serum levels of AOPPs
significantly correlated with serum Gd-IgA1 and% HAA. The relationship between these
biomarkers and clinical features at sampling and during follow-up was assessed in 62
patients with long-term follow-up. AOPPs and% HAA correlated with proteinuria at sampling
and independently associated with subsequent proteinuria. Levels of AOPPs correlated with …