The mRNA expression profile of cytokines connected to the regulation of melanocyte functioning in vitiligo skin biopsy samples and peripheral blood mononuclear …

E Reimann, K Kingo, M Karelson, P Reemann… - Human immunology, 2012 - Elsevier
The expression pattern of several genes associated with different processes in melanocytes,
including melanogenesis, is changed in vitiligo patients. We evaluated possible changes in
the expression of interleukin (IL)–10 family cytokines (IL26, IL-28A, IL28B, IL29), their
receptor subunits (IL20RB, IL22RA2, IL28RA), and genes potentially related to functioning of
melanocytes (MDM1, IFNA1, IFNB1, IFNG, and ICAM1) in the case of vitiligo. We observed
mRNA expression in vitiligo patients' and controls' skin and peripheral blood mononuclear …