Individualized IgE-based dosing of egg oral immunotherapy and the development of tolerance
BP Vickery, L Pons, M Kulis, P Steele, SM Jones… - Annals of Allergy …, 2010 - Elsevier
BACKGROUND: Hen's egg allergy is among the most common food allergies in childhood
and predicts later development of allergic disease. The optimal efficacy and mechanism (s)
of egg allergen immunotherapy are poorly understood. OBJECTIVE: To enhance
immunologic and clinical outcomes of egg oral immunotherapy (OIT) using a conditionally
increased dosing strategy. METHODS: In an open-label clinical trial of egg OIT, egg-allergic
children ingested daily doses of egg protein that were gradually increased based on the egg …
and predicts later development of allergic disease. The optimal efficacy and mechanism (s)
of egg allergen immunotherapy are poorly understood. OBJECTIVE: To enhance
immunologic and clinical outcomes of egg oral immunotherapy (OIT) using a conditionally
increased dosing strategy. METHODS: In an open-label clinical trial of egg OIT, egg-allergic
children ingested daily doses of egg protein that were gradually increased based on the egg …