The role of dendritic cells in food allergy
B Ruiter, WG Shreffler - Journal of Allergy and Clinical Immunology, 2012 - Elsevier
In recent years, our understanding of the initiation of TH2-type immunity has increased
significantly, yet the mechanism behind the induction of TH2 responses and allergic
sensitization to food antigens largely remains an enigma. Dendritic cells (DCs) were first
described almost 4 decades ago and have since been recognized as the most important
antigen-presenting cells and crucial in the induction of T-cell differentiation. Here we discuss
our current knowledge of the role of DCs in food allergy. In both murine models and allergic …
significantly, yet the mechanism behind the induction of TH2 responses and allergic
sensitization to food antigens largely remains an enigma. Dendritic cells (DCs) were first
described almost 4 decades ago and have since been recognized as the most important
antigen-presenting cells and crucial in the induction of T-cell differentiation. Here we discuss
our current knowledge of the role of DCs in food allergy. In both murine models and allergic …