[HTML][HTML] Sickle cell disease: old discoveries, new concepts, and future promise
PS Frenette, GF Atweh - The Journal of clinical investigation, 2007 - Am Soc Clin Investig
PS Frenette, GF Atweh
The Journal of clinical investigation, 2007•Am Soc Clin InvestigThe discovery of the molecular basis of sickle cell disease was an important landmark in
molecular medicine. The modern tools of molecular and cellular biology have refined our
understanding of its pathophysiology and facilitated the development of new therapies. In
this review, we discuss some of the important advances in this field and the impediments
that limit the impact of these advances.
molecular medicine. The modern tools of molecular and cellular biology have refined our
understanding of its pathophysiology and facilitated the development of new therapies. In
this review, we discuss some of the important advances in this field and the impediments
that limit the impact of these advances.
The discovery of the molecular basis of sickle cell disease was an important landmark in molecular medicine. The modern tools of molecular and cellular biology have refined our understanding of its pathophysiology and facilitated the development of new therapies. In this review, we discuss some of the important advances in this field and the impediments that limit the impact of these advances.
The Journal of Clinical Investigation