How fibroblast growth factor 23 works
S Liu, LD Quarles - Journal of the American Society of Nephrology, 2007 - journals.lww.com
There is a discontinuum of hereditary and acquired disorders of phosphate homeostasis that
are caused by either high or low circulating levels of the novel phosphaturic hormone
fibroblastic growth factor 23 (FGF23). Disorders that are caused by high circulating levels of
FGF23 are characterized by hypophosphatemia, decreased production of 1, 25-
dihydroxyvitamin D, and rickets/osteomalacia. On the other end of the spectrum are
disorders that are caused by low circulating levels of FGF23, which are characterized by …
are caused by either high or low circulating levels of the novel phosphaturic hormone
fibroblastic growth factor 23 (FGF23). Disorders that are caused by high circulating levels of
FGF23 are characterized by hypophosphatemia, decreased production of 1, 25-
dihydroxyvitamin D, and rickets/osteomalacia. On the other end of the spectrum are
disorders that are caused by low circulating levels of FGF23, which are characterized by …