Ectopic cardiac calcification associated with hyperparathyroidism in a boy with hypophosphatemic rickets
KC Moltz, AH Friedman, RA Nehgme… - Current opinion in …, 2001 - journals.lww.com
KC Moltz, AH Friedman, RA Nehgme, CS Kleinman, TO Carpenter
Current opinion in pediatrics, 2001•journals.lww.comAn adolescent with hypophosphatemic rickets developed cardiac calcifications in the
absence of hypercalcemia or elevation of the phosphocalcic product (the product of the total
serum calcium and phosphorus concentrations). Cardiac calcifications led to aortic and
mitral valve dysfunction, myocardial calcification, and arrhythmia. Hyperparathyroidism
probably played a significant role in the development of this complication, which
emphasizes the necessity for intermittent assessment of parathyroid status in individuals …
absence of hypercalcemia or elevation of the phosphocalcic product (the product of the total
serum calcium and phosphorus concentrations). Cardiac calcifications led to aortic and
mitral valve dysfunction, myocardial calcification, and arrhythmia. Hyperparathyroidism
probably played a significant role in the development of this complication, which
emphasizes the necessity for intermittent assessment of parathyroid status in individuals …
Abstract
An adolescent with hypophosphatemic rickets developed cardiac calcifications in the absence of hypercalcemia or elevation of the phosphocalcic product (the product of the total serum calcium and phosphorus concentrations). Cardiac calcifications led to aortic and mitral valve dysfunction, myocardial calcification, and arrhythmia. Hyperparathyroidism probably played a significant role in the development of this complication, which emphasizes the necessity for intermittent assessment of parathyroid status in individuals receiving medical therapy for hypophosphatemic rickets.
Lippincott Williams & Wilkins