[HTML][HTML] The role of IL-10 in immune regulation during M. tuberculosis infection
PS Redford, PJ Murray, A O'garra - Mucosal immunology, 2011 - Elsevier
During gaseous exchange the lungs are exposed to a vast variety of pathogens, allergens,
and innocuous particles. A feature of the lung immune response to lung-tropic aerosol-
transmitted bacteria such as Mycobacterium tuberculosis (Mtb) is a balanced immune
response that serves to restrict pathogen growth while not leading to host-mediated
collateral damage of the delicate lung tissues. One immune-limiting mechanism is the
inhibitory and anti-inflammatory cytokine interleukin (IL)-10. IL-10 is made by many …
and innocuous particles. A feature of the lung immune response to lung-tropic aerosol-
transmitted bacteria such as Mycobacterium tuberculosis (Mtb) is a balanced immune
response that serves to restrict pathogen growth while not leading to host-mediated
collateral damage of the delicate lung tissues. One immune-limiting mechanism is the
inhibitory and anti-inflammatory cytokine interleukin (IL)-10. IL-10 is made by many …