Molecular pathways underlying the modulation of T-type calcium channels by neurotransmitters and hormones

J Chemin, A Traboulsie, P Lory - Cell calcium, 2006 - Elsevier
Low-voltage-activated T-type calcium channels are expressed in various tissues, especially
in the brain, where they promote neuronal firing and are involved in slow wave sleep and
absence epilepsy. While the transduction pathways by which hormones and
neurotransmitters modulate high-voltage-activated calcium channels are beginning to be
unraveled, those implicated in T-type calcium channel regulation remain obscure. Several
neurotransmitters and hormones regulate native T-type calcium channels, although some …