Irradiation of the entire body and marrow transplantation: some observations and comments
ED Thomas, HL Lochte Jr, JW Ferrebee - Blood, 1959 - ashpublications.org
ED Thomas, HL Lochte Jr, JW Ferrebee
Blood, 1959•ashpublications.orgCase reports of 5 patients with acute leukemia receiving total-body irradiation and
intravenous infusion of normal marrow are presented. An eight-month follow-up on a
previously reported patient with chronic leukemia is included and a review of an individual
receiving nitrogen mustard and marrow is presented for comment. Of several patients
reported in this and in a previous communication only two may be said to have obtained
significant clinical benefit. Potential reasons for this incidence of improvement are advanced …
intravenous infusion of normal marrow are presented. An eight-month follow-up on a
previously reported patient with chronic leukemia is included and a review of an individual
receiving nitrogen mustard and marrow is presented for comment. Of several patients
reported in this and in a previous communication only two may be said to have obtained
significant clinical benefit. Potential reasons for this incidence of improvement are advanced …
Abstract
Case reports of 5 patients with acute leukemia receiving total-body irradiation and intravenous infusion of normal marrow are presented. An eight-month follow-up on a previously reported patient with chronic leukemia is included and a review of an individual receiving nitrogen mustard and marrow is presented for comment.
Of several patients reported in this and in a previous communication only two may be said to have obtained significant clinical benefit. Potential reasons for this incidence of improvement are advanced and the general subject of total-body irradiation and marrow replacement in man is discussed. Pitfalls and problems biologic and physical and the theory of their circumvention are analyzed.
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