Expression of high-affinity IgE receptors (FcϵRI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: Relationship to total …

BS Sihra, OM Kon, JA Grant, AB Kay - Journal of allergy and clinical …, 1997 - Elsevier
Background: High-affinity IgE receptors (FcϵRI) have been identified on peripheral blood
basophils, monocytes, and eosinophils; but the relative receptor expression on these cells
and their relationship to atopy are unclear. Objective: The aim of this study was to compare
FcϵRI expression on these cell types and assess their relationship to total serum IgE
concentrations in subjects with atopic asthma, rhinitis, or dermatitis compared with nonatopic
control subjects. Methods: Flow cytometry was used to evaluate FcϵRI expression by …