Expression of Chr9p21 genes CDKN2B (p15INK4b), CDKN2A (p16INK4a, p14ARF) and MTAP in human atherosclerotic plaque
LM Holdt, K Sass, G Gäbel, H Bergert, J Thiery… - Atherosclerosis, 2011 - Elsevier
OBJECTIVE: The pathophysiology underlying the chromosome (Chr) 9p21 locus of
atherosclerosis susceptibility is presently unknown. Here, we sought to determine whether
protein coding genes in the Chr9p21 region, ie cyclin-dependent kinase inhibitors CDKN2B
(p15INK4b), CDKN2A (p16INK4a, p14ARF) and methylthioadenosine phosphorylase
(MTAP) were expressed in human atherosclerotic lesions and whether expression was
correlated with lesion composition. METHODS AND RESULTS: Protein expression of …
atherosclerosis susceptibility is presently unknown. Here, we sought to determine whether
protein coding genes in the Chr9p21 region, ie cyclin-dependent kinase inhibitors CDKN2B
(p15INK4b), CDKN2A (p16INK4a, p14ARF) and methylthioadenosine phosphorylase
(MTAP) were expressed in human atherosclerotic lesions and whether expression was
correlated with lesion composition. METHODS AND RESULTS: Protein expression of …