Possible metformin-induced hepatotoxicity
E Kutoh - The American journal of geriatric pharmacotherapy, 2005 - Elsevier
BACKGROUND:: Metformin hydrochloride is widely used for the treatment of type 2 diabetes
mellitus (DM-2). Todate, only 2 cases of possible metformin-induced hepatotoxicity (acute
hepatitis) have been reported worldwide. OBJECTIVE:: The aim of this article was to report a
case of serious hepatotoxicity possibly associated with metformin use in an elderly patient
with DM-2. METHODS:: After receiving metformin 500 mg/d for 3 weeks, a 73-year-old
Japanese woman weighing 33. S kg with poorly controlled DM-2 presented with fatigue …
mellitus (DM-2). Todate, only 2 cases of possible metformin-induced hepatotoxicity (acute
hepatitis) have been reported worldwide. OBJECTIVE:: The aim of this article was to report a
case of serious hepatotoxicity possibly associated with metformin use in an elderly patient
with DM-2. METHODS:: After receiving metformin 500 mg/d for 3 weeks, a 73-year-old
Japanese woman weighing 33. S kg with poorly controlled DM-2 presented with fatigue …