[HTML][HTML] Chronic cardiac transplant arteriopathy in mice: relationship of alloantibody, C4d deposition and neointimal fibrosis
S Uehara, CM Chase, LD Cornell, JC Madsen… - American journal of …, 2007 - Elsevier
Murine heterotopic cardiac allografts were used to reveal some of the fundamental
interrelationships between donor-specific alloantibodies (DSA), chronic transplant
arteriopathy (CTA) and capillary C4d deposition. B10. BR recipients of B10. A hearts
developed transient DSA and C4d deposition that peaked on day 7 and became
undetectable at day 56 while CTA developed progressively. Male cardiac grafts in female
recipients showed similar degrees of CTA at day 56 but never developed DSA or C4d …
interrelationships between donor-specific alloantibodies (DSA), chronic transplant
arteriopathy (CTA) and capillary C4d deposition. B10. BR recipients of B10. A hearts
developed transient DSA and C4d deposition that peaked on day 7 and became
undetectable at day 56 while CTA developed progressively. Male cardiac grafts in female
recipients showed similar degrees of CTA at day 56 but never developed DSA or C4d …