Cell traffic and the lymphatic endothelium
LA Johnson, DG Jackson - Annals of the New York Academy of …, 2008 - Wiley Online Library
LA Johnson, DG Jackson
Annals of the New York Academy of Sciences, 2008•Wiley Online LibraryThe principal immune function of the afferent lymphatics is to bear antigen and leukocytes
from peripheral tissues to the draining lymph nodes. Recent research has shown that
passage of leukocytes into the afferent lymphatic capillaries is far from an indolent process;
rather it is carefully orchestrated by an array of adhesion molecules, as well as by
chemokines and their receptors. Here we review the current knowledge of leukocyte trans‐
lymphatic endothelial migration and its role in the development of an immune response.
from peripheral tissues to the draining lymph nodes. Recent research has shown that
passage of leukocytes into the afferent lymphatic capillaries is far from an indolent process;
rather it is carefully orchestrated by an array of adhesion molecules, as well as by
chemokines and their receptors. Here we review the current knowledge of leukocyte trans‐
lymphatic endothelial migration and its role in the development of an immune response.
The principal immune function of the afferent lymphatics is to bear antigen and leukocytes from peripheral tissues to the draining lymph nodes. Recent research has shown that passage of leukocytes into the afferent lymphatic capillaries is far from an indolent process; rather it is carefully orchestrated by an array of adhesion molecules, as well as by chemokines and their receptors. Here we review the current knowledge of leukocyte trans‐lymphatic endothelial migration and its role in the development of an immune response.
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