For many years, patient age, axillary lymph node status, tumor size, histological features
(especially histological grade and lymphovascular invasion), hormone receptor status, and
HER2 status have been the major factors used to categorize patients with breast cancer in
order to assess prognosis and determine the appropriate therapy. These factors are most
often viewed in combination to group patients into various risk categories. Although these
risk categories are useful for assessing prognosis and risk in groups of patients with breast …